Born in Indian Territory, she was the first woman to serve as principal chief of the Kaw Nation, holding the position from 1922 to 1934. She was trained as a nurse at Haskell Institute. As chief, Eads prioritized education and worked to reestablish the Kaw Agency, delivering a petition to the Commission of Indian Affairs in 1924. Her leadership focused on reviving the nation after a period of decline and advocating for her people's rights during a time of significant societal change.